Enbrel for post surgery pain

Discuss different Pain Management Options; Medication options including side effects and Worldwide variances in names etc.
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lindawright
Posts: 7
Joined: Sun Nov 21, 2010 6:40 pm

Enbrel for post surgery pain

Post by lindawright »

I am 5 months post surgery for pudendal and arbitrator intern us damage. surgeon is suggesting this injectable drug for one month trial. Drug is for RA treatment, drug depletes your immune system, so cannot take at same time with any other sickness symtoms. Has anyone tried this drug with any success whatever?
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ezer
Posts: 689
Joined: Sun Sep 19, 2010 6:53 am

Re: Enbrel for post surgery pain

Post by ezer »

There is a pilot study showing that Enbrel is efficacious for sciatica.
http://www.medscape.com/viewarticle/537922 (registration required)
Sep 16, 2004
Geneva, Switzerland - A pilot study of the TNF inhibitor etanercept (Enbrel, Wyeth) in patients with severe sciatica has shown that the drug appears to be effective, prompting further calls for randomized controlled trials in this potential new indication [ 1 ].
The side effects are a bit scary though especially with the flu season approaching.
The medication is horribly expensive (something like $3,000 for a month supply) and I am not sure if many insurance plans pay for it.
2002 PN pain started following a fall on a wet marble floor
2004 Headache in the pelvis clinic. Diagnosed with PNE by Drs. Jerome Weiss, Stephen Mann, and Rodney Anderson
2004-2007 PT, Botox, diagnosed with PNE by Dr. Sheldon Jordan
2010 MRN and 3T MRI showing PNE. Diagnosed with PNE by Dr. Aaron Filler. 2 failed PNE surgeries.
2011-2012 Horrific PN pain.
2013 Experimented with various Mind-body modalities
3/2014 Significantly better
11/2014 Cured. No pain whatsoever since
lindawright
Posts: 7
Joined: Sun Nov 21, 2010 6:40 pm

Re: Enbrel for post surgery pain

Post by lindawright »

Thanks for your reply. I see you also had surgery by Dr. Filler in 2010, did it work??
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ezer
Posts: 689
Joined: Sun Sep 19, 2010 6:53 am

Re: Enbrel for post surgery pain

Post by ezer »

I did remarkably well for 2 weeks then I slowly went back to my pre-surgery pain level. I think it is too early to judge based on other people's reports.
Did you experience any change?
2002 PN pain started following a fall on a wet marble floor
2004 Headache in the pelvis clinic. Diagnosed with PNE by Drs. Jerome Weiss, Stephen Mann, and Rodney Anderson
2004-2007 PT, Botox, diagnosed with PNE by Dr. Sheldon Jordan
2010 MRN and 3T MRI showing PNE. Diagnosed with PNE by Dr. Aaron Filler. 2 failed PNE surgeries.
2011-2012 Horrific PN pain.
2013 Experimented with various Mind-body modalities
3/2014 Significantly better
11/2014 Cured. No pain whatsoever since
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Karyn
Posts: 1655
Joined: Fri Sep 17, 2010 12:59 pm
Location: Lowell, MA

Re: Enbrel for post surgery pain

Post by Karyn »

Hi Linda,
I heard Enbrel advertised on TV last night for the first time. The entire ad consisted of very serious side effects that I didn't think would ever end, with a brief mention of how it's used to treat RA. I hope your doctor thoroughly discussed this drug with you. Personally, I find this drug scarier than PN.

http://www.drugs.com/sfx/enbrel-side-effects.html

Warm regards,
Karyn
Ultra Sound in 03/08 showed severely retroverted, detaching uterus with mulitple fibroids and ovarian cysts.
Pressure and pain in lower abdomen and groin area was unspeakable and devastating.
Total lap hysterectomy in 06/08, but damage was already done.
EMG testing in NH in 04/10 - bilateral PN and Ilioinguals
3T MRI at HSS, NY in 09/10
Bilateral TG surgery with Dr. Conway on 03/29/11. Bilat ilioinguinal & iliohypogastric neurectomy 03/12. TCD surgery 04/14.
lindawright
Posts: 7
Joined: Sun Nov 21, 2010 6:40 pm

Re: Enbrel for post surgery pain

Post by lindawright »

I never got any relief except from his painful injections, which numbed me down to my toes. He didn't wait for the numbness before he did the painful injections---I think if he had the injections wouldn't have been so painful. I am planning a "redo" surgery for one year after my surgery date. I know I am not the only Filler patient that has had to have this done. This is due to he not deadoning the nerves to stop firing pain signals.

I have also seen the Enbrel TV commercial. TV drug ads shouldn't be allowed. It does not mention the drug is an injection. I do have cancer in my family history that I worry about. My dr. wasn't worried by this, but I believe a trial on Enbrel could be the worst thing I can do at this time. Even over 5 years of PN pain, I don't think I am that desparate to signal Cancer in to my life also. I appreciate your thoughts on this Karyn.
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Karyn
Posts: 1655
Joined: Fri Sep 17, 2010 12:59 pm
Location: Lowell, MA

Re: Enbrel for post surgery pain

Post by Karyn »

Oh, my goodness, Linda! Thank you, thank you for not considering the Enbrel!!! I didn't even realize you had a family history of cancer! I was just horrified at all the different cancers it can induce! Whew! Understanding that everyone is different, and that some medications can be a godsend for certain people, I don't usually shoot my mouth off about these kinds of things. Was it actually Filler who suggested the injections?
I'm very sorry you're still in so much pain and are facing a redo. Are you going back to Filler? 5 months is still early for the healing process and I'm confident you'll get there! :)
Keeping you in my thoughts and wishing the very best for you!
Warm regards,
Karyn
Ultra Sound in 03/08 showed severely retroverted, detaching uterus with mulitple fibroids and ovarian cysts.
Pressure and pain in lower abdomen and groin area was unspeakable and devastating.
Total lap hysterectomy in 06/08, but damage was already done.
EMG testing in NH in 04/10 - bilateral PN and Ilioinguals
3T MRI at HSS, NY in 09/10
Bilateral TG surgery with Dr. Conway on 03/29/11. Bilat ilioinguinal & iliohypogastric neurectomy 03/12. TCD surgery 04/14.
lindawright
Posts: 7
Joined: Sun Nov 21, 2010 6:40 pm

Re: Enbrel for post surgery pain

Post by lindawright »

I think 5 months is too early also. I do intend to take it further at the one year mark. Filler is the one who suggested Enbrel. I have a PNE buddy who had her "redo" with another dr. than Filler and is excited with the results, she is one week out from her proceedure, I hope she keeps making progress. Other dr. did mention "redos" that he recognized as Fillers work.
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Charlie
Posts: 214
Joined: Fri Sep 17, 2010 11:48 pm

Re: Enbrel for post surgery pain

Post by Charlie »

Enbrel is a very powerful drug and I think people should be aware of the dangers of it. People have died from taking Enbrel.

http://www.aboutlawsuits.com/enbrel-120/

Another great concern is that Enbrel can actually cause nerve damage.

http://doublecheckmd.com/EffectsDetail. ... 5&eid=1883
Tried numerous medications as well as a long period of myofascial physical therapy combined with meditation/relaxation. My pelvic floor muscles are now normal and relaxed on exam ( confirmed by many Pelvic floor PTs) yet my pain remains the same. Also have intense leg pain. Deciding on next treatment.
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